Scientific References


1. Cheshenko, Natalia and others, “HVS activates AKT to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression”, in The Official Journal of the Federation of American Societies for Experimental Biology, March, 18, 2013:

2. Oldham ML and others, "A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter", in Nature, January, 20, 2016:

3. Beinerd, D. and others: “Structure of the viral Tap-inhibitor ICP47 induced by membrane association”, in Biochemistry, April, 15, 1997:

4. Neumanm L. and others, “The active domain of the herpes simplex virus protein ICP47: a potent inhibitor of the transporter associated with antigen processing”, in Journal of Molecular Biology, October, 3, 1997:

5. Phander R. and others, “Structure of the active domain of the herpes simplex virus protein ICP47 in water/sodium dodecyl sulfate solution determined by nuclear magnetic resonance spectroscopy”, in Biochemistry, 12, October 1999:

6. Kim Goldsmith and others, “Infected Cell Protein (ICP)47 Enhances Herpes Simplex Virus Neurovirulence by Blocking the CD8+ T Cell Response

7. Valentina Herbring and others, “A dual inhibition mechanism of herpesviral ICP47 arresting a conformationally thermostable TAP complex”, 15 Nov 2016,

8. J R Goss, M S Gold & J C Glorioso, “HSV vector-mediated modification of primary nociceptor afferents: an approach to inhibit chronic pain”, 09 Apr 2019,